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目的分析平阳县疑似预防接种异常反应(AEFI)的发生特征,评价AEFI监测系统运转情况及预防接种安全性。方法对平阳县2009—2013年AEFI监测系统中个案数据采用描述性流行病学方法进行分析。结果平阳县5年AEFI报告132例,男女比1.36∶1,其中一般反应73例、异常反应52例、偶合症3例及心因性反应4例。AEFI总报告发生率为7.77/10万。临床表现以发热红肿为主,占43.94%;过敏性皮疹占31.06%。结论平阳县AEFI发生率水平在试点省国家免疫规划疫苗估算的AEFI发生率范围内,AEFI监测系统敏感性较高且运转良好。
Objective To analyze the occurrence characteristics of suspected AEFI in Pingyang County and evaluate the operation of AEFI monitoring system and the vaccination safety. Methods Descriptive epidemiological methods were used to analyze the case data of AEFI surveillance system in Pingyang from 2009 to 2013. Results Five-year AEFI in Pingyang County reported 132 cases with a ratio of 1.36:1, of which 73 cases were general reaction, 52 cases were abnormal reaction, 3 cases were coupled disease and 4 cases were cardio-reaction. The total AEFI report was 7.77 / 100,000. The main clinical manifestations of fever, swelling, accounting for 43.94%; allergic skin rash 31.06%. Conclusion Level of AEFI in Pingyang County AEFI surveillance system is highly sensitive and works well within the estimated AEFI incidence of the national immunization program vaccine in the pilot provinces.