基因因素、内分泌系统和植物神经系统的状态及精神因素对功能性发声困难的发病，均具有重要意义。发声疲劳（由于滥用发声引起）属于功能性发声障碍，包括过强性发声困难和衰弱性发声困难。在发声疲劳患者中，常可见到上呼吸道粘膜有炎性改变。为研究发声疲劳的上呼吸道粘膜炎 Genes, endocrine and autonomic nervous system conditions and mental factors of functional dysarthria are of great significance. Fatigued sounds (caused by the abuse of sound) are functional vocal disturbances, including excessive vocal dysfunctions and debilitating vocal dysfunctions. Fatigue in patients with sound, often seen in the upper respiratory tract mucosal inflammatory changes. To study the upper respiratory mucositis of phonic fatigue