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结晶天花粉羊膜腔注射用于200例中期妊娠引产,疗效达99.5%。引产时间平均4.69±1.15天,出血量甚少,少于100ml者占90.5%。软产道损伤亦少,只有1例发生宫颈撕裂。加用地塞米松后,天花粉副反应明显减轻。体温小于37.5℃者占91.7%,无一例超过38.5℃。天花粉是异性蛋白,可能发生过敏反应,用后可以产生抗体,会影响再次用药疗效。将天花粉用羊膜腔注射,药物集中在羊膜腔内,进入血循环量甚微,再加用抗过敏药物,因此全身反应更减轻。
Crystallized pollen amniotic cavity injection of 200 cases of labor induction of midterm pregnancy, the effect of 99.5%. Induction time average 4.69 ± 1.15 days, very little bleeding, less than 100ml accounted for 90.5%. Soft birth canal injury is also less, only 1 case of cervical tear. Addition of dexamethasone, the TCS significantly reduced side effects. Body temperature less than 37.5 ℃ accounted for 91.7%, no case more than 38.5 ℃. TCS is a heterosexual protein, allergic reactions may occur, after use can produce antibodies, will affect the efficacy of re-medication. The TCS injection of amniotic membrane, the drug concentrated in the amniotic cavity, into the blood circulation is very small, plus anti-allergy drugs, so the systemic response is more reduced.