Stomatal Immunity: A Calcium Channel Essential for Pathogen-Induced Stomatal Closure

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Stomatal closure upon pathogen attack is a process involving Ca2+ entry into guard cells after perception of pathogen-associated molecular patterns (PAMPs), small microbial molecules recognized by plant receptors.A central role in this process is played by the signal transducing kinase BIK1 (Monaghan et al.,2015), which regulates cytosolic Ca2+ entry and reactive oxygen species production.However, the Ca2+ channel responsible for pathogen-induced cytosolic Ca2+ increase in guard cells remains unknown.Recently, in a Nature paper, Thor et al.(2020) reported the characterization of an Arabidopsis Ca2+-permeable channel,OSCA1.3, which is regulated by the BIK1 kinase to participate in this adaptive response (Figure 1).
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