纤维性海绵体炎一直是泌尿科医生治疗的难题,曾有许多治疗方法报告,但都效果不理想,钙通道阻滞剂可改变成纤维细胞的代谢,造成胶原的细胞外基质分泌减少.在本非随机剂量递升形式研究中,14人每两周在1%利多卡因麻醉后将10ml异搏定注入海绵体炎斑块,开始浓度为1mmol,每月剂量加强直至达到10mg,斑块需穿刺100～150次以使药物均匀分布于斑块中,共6月.主观上,斑 Fibrous cavernositis has been the treatment of urological problems, there have been many reports of treatment, but are not effective, calcium channel blockers can change the metabolism of fibroblasts, resulting in collagen secretion of extracellular matrix decreased in In this nonrandomized dose escalation study, 14 subjects were infused with 10 ml of verapamil into a cavernous plaque at a start of 1 mmol every two weeks after 1% lidocaine was anesthetized. The monthly dose was increased until reaching 10 mg. Puncture 100 to 150 times so that the drug is evenly distributed in the plaque, a total of 6 months. Subjective, spot