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目的 :研究乙型病毒性肝炎患者在病毒复制状态下及重型肝炎患者的免疫功能紊乱情况。方法 :应用流式细胞仪检测T淋巴细胞亚群 ,ELISA法检测HBV m。结果 :乙型病毒性肝炎患者CD4+/CD8+值较正常对照组下降。在乙型肝炎病毒复制组为 0 .97± 0 .42 ,在重型肝炎组为 1 .0 9± 0 .2 8。结论 :乙型病毒性肝炎为免疫损伤所致 ,在重型肝炎及乙型肝炎病毒复制状态下存在严重免疫功能紊乱。
Objective: To study the immune dysfunction of patients with viral hepatitis B virus replication and severe hepatitis. Methods: T lymphocyte subsets were detected by flow cytometry and HBV m was detected by ELISA. Results: The CD4 + / CD8 + of patients with viral hepatitis B was lower than that of the control group. In the hepatitis B virus replication group was 0.97 ± 0.42, in the severe hepatitis group was 1.90 ± 0.28. Conclusion: Hepatitis B virus is caused by immune injury, and there is severe immune dysfunction in severe hepatitis and hepatitis B virus replication.