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目的探讨经尿道膀胱肿瘤电切术(TURBT)术后患者尿路感染原因,以期为临床TURBT术后尿路感染的预防治疗提供帮助。方法回顾性分析2009年1月-2012年12月行TURBT住院患者的临床资料、尿路感染的发生率及其影响因素、病原菌分布,采用SPSS17.0统计软件进行数据分析。结果 213例行TURBT患者术后发生尿路感染60例,感染率28.17%;共分离出68株病原菌,革兰阴性菌50株占73.5%,革兰阳性菌18株占26.5%,其中以大肠埃希菌最为常见占51.5%,其次是肺炎克雷伯菌和肠球菌属,分别占17.6%、4.4%,未分离出真菌;年龄>60岁、肿瘤位点多发患者、有糖尿病史、术前有留置导管、白细胞数低、术前使用抗菌药物数量少是TURBT术后尿路感染的危险因素(P<0.05),而性别、细胞分型以及慢性支气管炎史对其影响不明显。结论 TURBT术后感染的发生率较高,以革兰阴性菌感染为主,多种相关因素与TURBT术后发生感染有关,性别、细胞分型以及慢性支气管炎史与术后发生感染无显著相关。
Objective To investigate the causes of urinary tract infection in patients after transurethral resection of bladder tumor (TURBT), in order to provide help for the prevention and treatment of urinary tract infection after TURBT. Methods The clinical data of hospitalized patients with TURBT from January 2009 to December 2012 were retrospectively analyzed. The incidence of urinary tract infection, its influencing factors and pathogenic bacteria distribution were analyzed retrospectively. Data were analyzed by SPSS17.0 statistical software. Results TURBT occurred in 213 patients with urinary tract infection in 60 cases, the infection rate was 28.17%. A total of 68 pathogens were isolated, including 50 strains of Gram-negative bacteria accounting for 73.5% and 18 strains of Gram-positive bacteria accounting for 26.5% Escherichia coli most commonly accounted for 51.5%, followed by Klebsiella pneumoniae and Enterococcus, accounting for 17.6%, 4.4%, respectively, did not isolate fungi; age> 60 years old, patients with multiple tumor sites, history of diabetes, There were indwelling catheters, low number of white blood cells and less antimicrobial drugs preoperatively were risk factors for urinary tract infection after TURBT (P <0.05), while gender, cell type and history of chronic bronchitis had no significant effect. Conclusions The incidence of postoperative TURBT infection is high, with Gram-negative bacteria as the main infection. Various related factors are related to the infection after TURBT. The gender, cell type and the history of chronic bronchitis have no significant correlation with postoperative infection .