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文章在查阅国内外相关文献的基础上,对中医药黄酮类化合物抗宫颈癌作用机制的研究进展综述。中医药黄酮类化合物抗人宫颈癌的作用机制主要有抑制宫颈癌细胞增殖及促进其凋亡、调节信号传导,抑制肿瘤细胞的侵袭和转移能力、逆转Hela细胞株多药耐药性,免疫增强作用,能够增强抗氧化能力和清除自由基的能力。对中医药抗宫颈癌作用机制的研究,阐明其物质基础以及将为开发更安全有效的抗宫颈癌新药提供新的思路。
Based on the review of relevant literatures at home and abroad, the article reviews the research progress on the mechanism of flavonoids against cervical cancer in traditional Chinese medicine. Traditional Chinese medicine flavonoids anti-human cervical cancer mechanisms mainly inhibit cervical cancer cell proliferation and promote apoptosis, regulate signal transduction, inhibition of tumor cell invasion and metastasis, reversal of Hela cell line multidrug resistance, immune enhancement Role, can enhance the antioxidant capacity and the ability to scavenge free radicals. To study the mechanism of action of Chinese medicine on cervical cancer, to clarify its material basis and to provide new ideas for the development of safer and more effective anti-cervical cancer drugs.