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越南民主共和国从1959年起广泛开展对新生儿的卡介苗接种工作。由于气候炎热,菌苗的保存和运输成为一个难以解决的问题,因此必须寻找一种不具有活菌苗的麻烦和缺点的有效菌苗。河内结核病研究所与微生物研究所合作,经数年来的研究,证明了用43℃热度杀死的卡介苗,用与活卡介苗相同的剂量接种,可以获得同样的免疫力,从而为在越南广大城乡推行大规模卡介苗接种创造了有利条件。1960年
Since 1959, the Democratic Republic of Vietnam has carried out a wide range of BCG vaccination programs on newborns. Due to the hot weather, the preservation and transport of the bacterin become a difficult problem to be solved. Therefore, it is necessary to find an effective bacterin that does not have the troubles and disadvantages of the live bacterin. In collaboration with the Institute of Microbiology, the Institute for Tuberculosis and Tuberculosis in Hanoi has, over the years, demonstrated that BCG killed with heat at 43 ° C shows the same immunity as vaccinated with live BCG to achieve the same immunity for urban and rural areas in Vietnam Large-scale BCG vaccination has created favorable conditions. 1960