隐球菌是一种主要侵犯人中枢神经系统,引起隐球菌病的深部真菌〔1〕。隐球菌属包括17个种和8个变种,其中新型隐球菌是主要的致病菌。新生隐球菌是广泛存在于自然环境中,其中以从鸽粪中分离出的新生隐球菌被认为是人类感染的最重要来源〔2〕。近年来该病的发病率呈明显上升趋势, Cryptococcus is a major invasion of the central nervous system, causing cryptococcosis deep fungus 〔1〕. Cryptococcus includes 17 species and 8 varieties, of which Cryptococcus neoformans is the main pathogen. Cryptococcus neoformans is widespread in the natural environment, of which Cryptococcus neoformans isolated from pigeon feces is considered to be the most important source of human infection [2]. In recent years, the incidence of the disease showed a clear upward trend,