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目的:观察思密达和654-2保留灌肠治疗小儿秋季腹泻的疗效。方法:将200例小儿秋季腹泻患儿随机分成两组,对照组100例予利巴韦林注射液静滴,1次/d,观察组100例加用思密达和654-2保留灌肠,1次/d。结果:观察组显效62例(62.0%),有效33例(33.0%),无效5例(5.0%),总有效率95.0%;对照组显效48例(48.0%),有效率38例(38.0%),无效14例(14.0%),总有效率为86.0%。两组比较,治疗组显效率及总有效率均高于对照组(P均<0.05)。结论:在常规抗病毒治疗的基础上加用思密达和654-2保留灌肠,疗效好于单用利巴韦林。
Objective: To observe the efficacy of Smecta and 654-2 retention enema in the treatment of infantile autumn diarrhea. Methods: Two hundred children with infantile autumn diarrhea were randomly divided into two groups. The control group received intravenous ribavirin injection once a day for 100 cases, and the control group received Smecta and 654-2 retention enema. 1 time / d. Results: The observation group was effective in 62 cases (62.0%), effective in 33 cases (33.0%), ineffective in 5 cases (5.0%), the total effective rate was 95.0%; in the control group, 48 cases %), Invalid in 14 cases (14.0%), the total effective rate was 86.0%. The two groups, the treatment group markedly effective and total effective rate was higher than the control group (P all <0.05). Conclusion: The combination of Smectite and 654-2 retention enema on the basis of conventional antiviral therapy is more effective than ribavirin alone.