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目的 探讨米非司酮与米索前列醇联合用于中期妊娠引产的效果 ,并与用利凡诺引产的疗效进行比较。方法 选用中期妊娠要求引产的妇女 6 5 5例 ,随机分为观察组 30 0例和对照组 35 5例 ,观察组用米非司酮联合米索前列醇 ,对照组单用利凡诺。结果 两组从用药到出现宫缩时间 ,宫缩至胎盘排出时间 ,胎盘、胎膜残留 ,子宫出血等比较均有显著意义 (P <0 .0 1)。结论 米非司酮与米索前列醇联合应用是较理想的引产方法。
Objective To investigate the effect of mifepristone combined with misoprostol on induction of labor in the second trimester of pregnancy and to compare the efficacy of rivanol with induction of labor. Methods 655 women were enrolled in the second trimester pregnancy requiring induction of labor. They were randomly divided into the observation group of 30 0 cases and the control group of 35 5 cases. The observation group was treated with mifepristone plus misoprostol. The control group received rivanol alone. Results There were significant differences between the two groups in terms of time from administration to contractions, contractions from contractions to placenta, placenta, residual fetal membranes and bleeding from the uterus (P <0.01). Conclusion The combination of mifepristone and misoprostol is an ideal induction of labor.