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目的：探讨新生儿缺氧缺血性脑病（ＨｙｐｏｘｉｃＩｓｃｈｅｍｉｃＥｎｃｅｐｈａｌｏｐａｔｈｙ，简称ＨＩＥ）的程度与预后的关系。材料和方法：收集有围产期窒息史、ＣＴ诊断为ＨＩＥ的２７例患儿分别于３个月、１岁、１岁半进行了ＣＴ复查和临床智能发育随访。结果：ＣＴ复查４例有外部性脑积水，５例幕上脑室扩大，其中３例伴局限性脑萎缩，另２例死亡；余１６例ＣＴ表现正常。临床智能随访，８例有发育异常，占存活病例３２％。结论：１、ＨＩＥ预后与ＣＴ分度密切相关。轻中者预后良好，重患者预后差。２、早产窒息儿颅内病变重，如脑质弥漫性低密度灶伴有出血或脑室内出血预后差。
Objective: To investigate the relationship between the degree and prognosis of neonatal hypoxic-ischemic encephalopathy (HIE). Materials and Methods: Twenty-seven children with history of perinatal asphyxia and CT diagnosis of HIE were followed up for CT review and clinical intelligence development at 3 months, 1 year and 1 year and 1 year and half respectively. Results: 4 cases had external hydrocephalus after CT examination, 5 cases had supratentorial ventricles enlarged, 3 cases had localized brain atrophy and 2 cases died. The other 16 cases showed normal CT. Clinical intelligence follow-up, 8 patients with dysplasia, accounting for 32% of the cases of survival. Conclusions: 1, HIE prognosis and CT classification are closely related. The light of the prognosis is good, poor prognosis of patients. 2, premature children with asphyxia exacerbation of intracranial lesions, such as diffuse low density brain with bleeding or intraventricular hemorrhage with poor prognosis.