目前防治孕妇感染抗性恶性疟尚乏理想的药物。本研究将两种药物联用方案与常规氯喹疗法进行了比较,旨在确定哪种治疗方案对清除疟原虫最有效,治疗后能持续多长时间不再感染,并比较不同孕情对治疗结果的影响。1988年5～7月,从肯尼亚Kakamega区Mumias的St Mary医院产前检查怀孕20～36周的妇女(988名)中选出恶性疟患者182名,其中158名(初孕妇89名,经产孕妇69名)进入最终分析;从第二寄宿学校已达 The current prevention and treatment of pregnant women infected with falciparum malaria is still an ideal drug. This study compared two regimens with conventional chloroquine therapy to determine which treatment regimen was most effective in eluting malaria parasite and how long the treatment would last without further infection and to compare treatment outcomes with different pregnancies Impact. From May to July 1988, 182 malaria patients were selected from 986 pregnant women (988 pregnant women) at St Mary Hospital, Mumias, Kakamega, Kenya, 158 of whom (89 in the first trimester) 69 pregnant women) entered the final analysis; from the second boarding school reached