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目的探讨腰臀比(WHR)和体质指数(BMI)与代谢综合征(MS)的相关性。方法选择2007年1月至2008年12月期间进行健康体检的上海保税区企业人群668例作为调查对象,根据BMI和WHR分为A组正常体重正常体型、B组正常体重异常体型、C组异常体重正常体型、D组异常体重异常体型,进行MS流行病学调查,并分析WHR和BMI与高血压、高血糖、血脂异常等代谢异常的患病关系。结果调查对象BMI异常检出率为49.1%(标化率40.30%),WHR异常检出率为53.0%(标化率54.75%),随年龄的增长肥胖患病率呈上升趋势;与A组相比,B组、D组的高血压、高血糖、血脂异常及MS患病率以及合并2项以上代谢异常情况均明显增高(P<0.05),而C组人群仅高血压及MS的患病率明显增高(P<0.05),B组、C组、D组人群MS的患病风险均高于A组,OR值分别为11.581(95%CI:1.277～105.044)、16.600(95%CI:1.822～151.224)、83.000(95%CI:11.419～603.289)。结论 WHR、BMI异常可增加MS的患病风险,WHR对代谢异常的影响比BMI更高,两者结合可明显提高MS风险预测的特异性和敏感性,应将WHR、BMI作为MS早期防治的控制指标。
Objective To investigate the relationship between WHR and BMI and metabolic syndrome (MS). Methods Six hundred and eighty-eight patients in Shanghai Free Trade Zone who conducted physical examination from January 2007 to December 2008 were selected as the subjects. According to BMI and WHR, they were divided into normal body weight of group A, normal body weight of group B, abnormal body weight of group C Normal body weight, abnormal body weight in group D, MS epidemiological investigation, and analysis of WHR and BMI and hypertension, hyperglycemia, dyslipidemia and other metabolic abnormalities. Results The detection rate of abnormal BMI was 49.1% (standardized rate 40.30%) and the prevalence of WHR abnormality was 53.0% (standardized rate 54.75%). The prevalence of obesity increased with the increase of age. Compared with group A Compared with those in group B and group D, the prevalence of hypertension, hyperglycemia, dyslipidemia and MS were significantly higher than those in group B (P <0.05), while those in group C were only hypertension and MS The prevalence of MS in group B, C and D was significantly higher than that in group A (OR = 11.581, 95% CI: 1.277-105.044, 16.600, 95% CI : 1.822-151.224), 83.000 (95% CI: 11.419-603.289). Conclusion The abnormal WHR and BMI can increase the risk of MS. WHR has a higher impact on metabolic abnormalities than BMI. The combination of the two can significantly improve the specificity and sensitivity of MS risk prediction. WHR and BMI should be used as early prevention and treatment of MS Control indicators.