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近年来,越来越多研究认为哮喘与脂溶性维生素有关。研究提示维生素E具有保护线粒体、抗氧化、抑制肺泡巨噬细胞活化、抑制细胞信号转导等作用;哮喘急性发作时,血清维生素E水平普遍降低;胎儿时期缺乏α-维生素E导致胎肺发育落后;维生素E异构体对气道炎症的相对抑制效力依次为γ生育三烯酚(γ-TE)>γ-生育酚>α-生育酚。本文就维生素E与支气管哮喘的关系进行综述。
In recent years, more and more studies have suggested that asthma is related to fat-soluble vitamins. Studies have shown that vitamin E has the protection of mitochondria, anti-oxidation, inhibition of alveolar macrophage activation, inhibition of cell signal transduction; acute exacerbation of asthma, serum vitamin E levels are generally lower; lack of fetal vitamin A lead to fetal lung development lag ; The relative inhibitory potencies of vitamin E isomers on airway inflammation were γ tocotrienol (γ-TE)> γ-tocopherol> α-tocopherol. This article reviews the relationship between vitamin E and bronchial asthma.