喉角化病是罕见病,迄今国内文献报道尚少,一且遇到常易误诊误治,1987年我们遇到一例,经激光治疗好转,随访二年多无复发,现报告如下。患者陈××,男,59岁,门诊号44604.主诉:声嘶半年多,于1987年2月27日就诊,过去有烟酒嗜好30余年。咽部检查:粘膜充血,扁桃体肿大Ⅱ°。间接喉镜检查:两侧声带肥厚,其表面有白色长片状角化物.颇似云片糕样分别盖在两侧声带上,声门变狭,闭合不紧,声门下无异常.疑诊喉部新生物,先后取活体组织送病检3次,报告均为声带鳞状上皮伴过度角化.全身体检,除有萎缩性胃炎外,余无异常。最后确诊为喉角化病。给庆大霉素加地塞米松超声雾化和服维生素等治疗1个多月,无好转,声嘶反而加重,声带上角化物增多、增厚。于1987年8月28日停用其他治 Throat disease is a rare disease, up to now domestic literature is still less, and often encounter misdiagnosis and misdiagnosis, in 1987 we encountered a case, the laser treatment improved, no recurrence of more than two years follow-up, are as follows. Patient Chen × ×, male, 59 years old, outpatient number 44604. Chief complaint: hoarseness more than six months, on February 27, 1987 for treatment, in the past have alcoholic drinks and tobacco more than 30 years. Pharyngeal examination: mucosal congestion, tonsil enlargement Ⅱ °. Indirect laryngoscopy: Vocal cord hypertrophy on both sides of the surface of the white long sheet of keratin. Similar to the cloud cake were covered on both sides of the vocal cords, glottis narrow, closed not tight, no abnormality under the supraglottic. Laryngeal new creatures, has taken the living tissue sent to the pathological examination 3 times, the report is accompanied by squamous hyperkeratosis .Systemic examination, except for atrophic gastritis, I no exception. Finally diagnosed as laryngeal disease. To gentamicin plus dexamethasone ultrasonic atomization and taking vitamins and other treatment more than 1 month, no improvement, hoarseness but aggravated, vocal cord keratosis increased, thickening. On August 28, 1987 to disable other treatment