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本文应用图像分析技术 ,对我院 1 996～ 1 998年住院手术治疗的 68例甲状腺癌 ( thyroidcarcinoma,TC)、2 0例甲状腺腺瘤 ( adenoma,AD)、6例腺瘤伴乳头状增生 ( adenoma and popillary,APP)进行了 DNA含量及细胞核形态参数检测。结果显示 :DNA指数、DNA倍体及细胞核形态参数三种检测 ,TC与 AD组对比有显著性差异 ( P <0 .0 1 ) ,TC组与 APP组对比也有明显差异 ( P <0 .0 5)。它提示用针吸病理检查同时追加上述三种检测 ,将是术前鉴别诊断的参数之一。探讨了这三种检测结果与甲状腺癌预后因素的关系及潜在的应用价值。
In this paper, 68 cases of thyroid carcinoma (TC), 20 cases of adenoma (AD), 6 cases of adenoma with papillary hyperplasia (PTCA) in our hospital from 1996 to 1998 were analyzed with image analysis technique. adenoma and popillary, APP) DNA content and nuclear morphological parameters were detected. The results showed that there were significant differences between TC and AD groups (P <0. 01) and between TC group and APP group (P <0. 0 5). It prompts the needle suction pathological examination while adding the above three tests, will be one of the parameters of differential diagnosis before surgery. Explore the relationship between these three test results and prognosis of thyroid cancer and its potential value.