论文部分内容阅读
目的:观察越鞠保和丸治疗抑郁症的疗效及其对血浆5-HT含量的影响。方法:治疗组口服中药越鞠保和丸,对照组应用氟西汀。于治疗前后应用汉密尔顿抑郁量表(HAMD)评定药物疗效,并同时检测两组治疗前后血浆5-HT含量。结果:两组在HMAD抑郁评分方面,两组治疗后与治疗前比较,均有统计学意义(P<0.01),总体疗效两组无显著性差异(P>0.05)。两组治疗后血浆5-HT含量均较治疗前有明显升高,前后比较均有统计学意义(P<0.01),两者治疗后比较无显著性差异。结论:中药治疗能使患者抑郁症状明显改善,有利于提高患者的生活质量;对血浆5-HT含量有影响,进一步说明血浆5-HT含量与抑郁症的发生具有相关性。
Objective: To observe the therapeutic effect of Yueju Baohewan on depression and its effect on plasma 5-HT content. Methods: The treatment group oral Chinese medicine Yue Ju Bao and pills, the control group fluoxetine. Before and after treatment with the Hamilton Depression Scale (HAMD) to assess the efficacy of drugs, and at the same time test two groups before and after treatment of plasma 5-HT content. Results: There was no significant difference between the two groups in the HMAD depression score (P <0.01) after treatment and before treatment. There was no significant difference between the two groups (P> 0.05). The plasma 5-HT levels in both groups were significantly higher than those before treatment (P <0.01), and there was no significant difference between the two groups after treatment. Conclusion: Chinese medicine treatment can significantly improve the symptoms of depression in patients, help to improve the quality of life of patients; 5-HT content of plasma has an impact on further elucidation of plasma 5-HT content and depression are associated with the occurrence.