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四、遗传毒性化合物的鉴定(一) 这一问题的性质为了评价饮水遗传毒物对健康的危险性,迫切要求对遗传毒物的鉴定进行研究。但要阐明某些特定化合物所造成的诱变性水平是困难的。其原因可归纳为:1.饮水中化学物的数量极大。Lucas(1985)在一项调查中,已从饮水中鉴定出有机化学物近1100种,且尚有一倍的有机物未获鉴定;大多数已鉴定的污染物其浓度<1μg/L;2.在已鉴定出的化合物中,仅1/3的化合物曾作过诱
Identification of Genotoxic Compounds 1. The Nature of the Problem In order to assess the health risks of drinking water genetic toxins, there is an urgent need to study the identification of genetic toxicants. However, it is difficult to elucidate the level of mutagenicity caused by certain specific compounds. The reasons can be summarized as follows: 1. There is a great amount of chemicals in drinking water. In a survey, Lucas (1985) identified nearly 1,100 organic chemicals from drinking water and twice the amount of organic matter was unidentified; the concentration of most of the identified contaminants was <1 μg / L; Only one-third of the compounds identified have been induced