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目的探讨戊型病毒性肝炎(戊肝)的危险因素。方法以112例戊型病毒性肝炎患者为病例组,以其同事(学)、配偶或邻居作为对照,应用病例对照研究方法收集流行病学史、相关卫生行为等,采用单因素、多因素Lo-gistic回归等分析戊肝发病的危险因素。结果单因素分析表明,与戊肝发病相关的危险因素有外餐史、不洁饮食史、不良卫生习惯、抽烟习惯、有特殊业余嗜好、慢性乙肝或HBsAg携带史等;多因素Logistic回归分析,差异有统计学意义的有外餐史(OR=2.42,95%CI=1.27~4.59)、不良卫生习惯(OR=2.18,95%CI=1.19~3.99)和慢性乙肝或HBsAg携带史(OR=5.54,95%CI=2.24~13.70)。结论外餐史、不良卫生习惯是戊型病毒性肝炎的危险因素,既往有乙肝病史或HBsAg携带史的人群是戊肝发病高危人群,应加强保护。
Objective To explore the risk factors of hepatitis E (hepatitis E). Methods A total of 112 cases of patients with viral hepatitis E were selected as the case group and their colleagues, spouses and neighbors were used as controls. The epidemiological history and related health behaviors were collected by case-control study. Single-factor and multiple-factor Lo -gistic regression analysis of the risk factors of hepatitis E pathogenesis. Results Univariate analysis showed that the risk factors related to the pathogenesis of hepatitis E were foreign food history, unclean diet history, unhealthy habits, smoking habit, special hobby habits, chronic hepatitis B or HBsAg carrier history, etc; multivariate Logistic regression analysis, The differences were statistically significant with history of eating (OR = 2.42, 95% CI = 1.27-4.59), poor hygiene (OR = 2.18,95% CI = 1.19-3.99), and history of chronic hepatitis B or HBsAg carriage (OR = 5.54, 95% CI = 2.24 ~ 13.70). Conclusion Foreign food history and bad hygiene habits are the risk factors for type-V hepatitis. The population with previous history of hepatitis B or HBsAg-carrying is the high-risk population of hepatitis E and should be protected.