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我院内分泌实验室在对1700例患者行促甲状腺激素释放激素(TRH)静脉注射时,有1例甲状腺功能减退症患者发生了严重副作用,现报告如下。患女,28岁,因静脉注射TRH,1h 后突然寒战、四肢抽搐入院。4d 前患者发现颈粗而就诊,在实验室行TRH 兴奋试验,用TRH0.3mg+生理盐水2ml 缓慢静注,约半小时后感觉恶心、头晕,至1h 后突然寒战,四肢抽搐持续约5min,无意识障碍,随即将病人平放,当时Bp16/10.5kPa,HR100次/min(?)并立即入院。入院后查体:T40℃,P
In our hospital endocrine laboratory in 1700 cases of thyroid stimulating hormone releasing hormone (TRH) intravenous injection, a case of hypothyroidism in patients with serious side effects, are as follows. Suffering from women, 28 years old, due to intravenous injection of TRH, sudden chills after 1h, convulsions admitted to the limbs. 4d before the discovery of coarse neck and treatment, TRH excited test in the laboratory TRH0.3mg + saline 2ml intravenous infusion of about half an hour after nausea, dizziness, sudden chills to 1h, convulsions limbs continued for about 5min, unconscious Obstacles, then the patient lay flat, then Bp16 / 10.5kPa, HR100 beats / min (?) And was admitted immediately. After admission examination: T40 ℃, P