血管扩张剂用于充血性心力衰竭病人以解除外周血管收缩。硝酸盐是最初使用的药物,以后又引入动脉扩张剂和α肾上腺素阻滞剂。最近,又提出血管紧张素转换酶抑制剂、钙通道阻滞剂、β受体激动剂、磷酸二酯酶抑制剂。在过去10-20yr内大约共应用40多种血管扩张剂治疗心衰。 Vasodilators are used in patients with congestive heart failure to relieve peripheral vasoconstriction. Nitrate was the initial drug used, and later arterial dilators and alpha-adrenergic blockers were introduced. Recently, angiotensin converting enzyme inhibitors, calcium channel blockers, beta receptor agonists and phosphodiesterase inhibitors have also been proposed. Approximately 40 vasodilators have been used to treat heart failure in the past 10-20 yr.