人淋巴细胞表面具有绵羊红细胞受体(E受体),能与绵羊红细胞自发形成E花环,许多论据证实形成E花环的细胞为T淋巴细胞。T淋巴细胞为异质性,部分细胞对SRBC具有高度的亲和力,可形成早期或活性E花环。形成这类花环的细胞(E_aRFC)可能是一组T细胞的特殊亚群,它代表具有免疫活性功能的效应细胞。 Human lymphocytes have sheep erythrocyte receptors (E receptors) on their lymphocytes that spontaneously form E rosette with sheep erythrocytes, and many arguments confirm that the cells that form the E rosette are T lymphocytes. T lymphocytes are heterogeneous, some cells have a high affinity for SRBC, can form early or reactive E-rosette. The cells forming such a rosette (E_aRFC) may be a special subset of T cells that represent effector cells that function immunologically.