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小细胞肺癌以侵袭性高、容易出现远处转移而著称,预后极差。化疗是各期小细胞肺癌治疗的基石所在。与化疗相比,分子靶向治疗具有高效、低毒的特点,是目前肿瘤治疗发展的新方向。近年来,一些分子靶向药物在治疗中小细胞肺癌患者治疗中进行了临床研究。本文将对小细胞肺癌分子靶向治疗的重要分子靶点和相应药物进行论述。
Small cell lung cancer with high invasion, prone to distant metastasis known, the prognosis is poor. Chemotherapy is the cornerstone of treatment of all stages of small cell lung cancer. Compared with chemotherapy, molecular targeted therapy has the characteristics of high efficiency and low toxicity, which is the new direction of the development of cancer therapy. In recent years, some molecular targeted drugs have been clinically studied in the treatment of patients with small-cell lung cancer. This article discusses molecular targeted therapy of small cell lung cancer and its corresponding molecular targets.