前列腺特异性抗原(t-PSA)是仅由前列腺上皮细胞分泌的丝氨酸蛋白酶,具有很好的组织特异性。目前,广泛应用于前列腺癌的早期诊断和鉴别诊断,具有较高的特异性和敏感性。我们实验室通过十年的检测发现,血清总前列腺原(PSA)是前列腺组织特异,而非前列腺癌特异,在前列腺的增生、感染、炎症等疾病时,同样可以使血清升高。 Prostate-specific antigen (t-PSA) is a serine protease secreted by prostate epithelial cells alone and has good tissue specificity. At present, it is widely used in the early diagnosis and differential diagnosis of prostate cancer, with high specificity and sensitivity. A decade of tests in our laboratory found that serum total prostatic hyperplasia (PSA) is prostate tissue-specific rather than prostate-specific and can also raise serum levels in prostatic hyperplasia, infections and inflammation.