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目的:检测甲砜霉素和盐酸左氧氟沙星对吉林地区泌尿生殖道感染的敏感性,为临床治疗提供依据。方法:采用微量稀释法。先配制甲砜霉素和盐酸左氧氟沙星含量为128 mg/L溶液,再制备药敏板,用培养基作对照。结果:检测58株支原体对两种药物的最低抑菌浓度(MIC)都很敏感,但左氧氟沙星比甲砜霉素更敏感,MIC值有显著性差异(χ2=6.38,P<0.05)。结论:吉林地区泌尿生殖道支原体引起的非淋菌性尿道炎(阴道炎)可用甲砜霉素和盐酸左氧氟沙星治疗。应用盐酸左氧氟沙星比甲砜霉素疗效更好。
Objective: To detect the sensitivity of thiamphenicol and levofloxacin hydrochloride to genitourinary tract infection in Jilin, and to provide the basis for clinical treatment. Methods: Using micro-dilution method. The first preparation of thiamphenicol and levofloxacin hydrochloride content of 128 mg / L solution, and then prepare sensitive plate, with the medium as a control. Results: 58 strains of Mycoplasma were sensitive to the minimum inhibitory concentration (MIC) of the two drugs. However, levofloxacin was more sensitive than thiamphenicol and the MIC value was significantly different (χ2 = 6.38, P <0.05). Conclusion: Non-gonococcal urethritis (vaginitis) caused by genitourinary tract mycoplasma in Jilin can be treated with thiamphenicol and levofloxacin hydrochloride. Levofloxacin hydrochloride is better than thiamphenicol.