非洛地平对老年高血压无痛性心肌缺血的影响

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目的:观察非洛地平缓释片(Felodipine-ER)对老年高血压病人无痛性心肌缺血(SMI)的影响。方法:38例老年高血压伴SMI病人采用单项药物Felodipine-ER5~10mg,每天1次口服,疗程4周。结果:降压总有效率86.8%;ECG总改善率55.3%,缺血型ST段压低明显改善;对心率,血甘油三酯、总胆固醇、低密度脂蛋白胆固醇无明显影响,而高密度脂蛋白胆固醇比治疗前明显增加。结论:Felodipine-ER可改善老年高血压病的无痛性心肌缺血,降低血压。 Objective: To observe the effect of Felodipine-ER on painless myocardial ischemia (MI) in elderly hypertensive patients. Methods: 38 elderly hypertensive patients with SMI were treated with single drug Felodipine-ER 5 ~ 10 mg once daily for 4 weeks. Results: The total effective rate of decompression was 86.8%; the total improvement rate of ECG was 55.3%; the depression of ischemic ST segment was significantly improved; but no significant effect on heart rate, blood triglyceride, total cholesterol and low density lipoprotein cholesterol, The high-density lipoprotein cholesterol than before treatment increased significantly. Conclusion: Felodipine-ER can improve painless myocardial ischemia and reduce blood pressure in elderly patients with hypertension.
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