目的:观察动脉栓塞化疗联合钬激光切除治疗多发性膀胱肿瘤的疗效。方法:36例多发性膀胱肿瘤患者先行髂内动脉灌注栓塞化疗,4~6 d后经尿道膀胱肿瘤钬激光切除术,术后常规吡柔比星膀胱内灌注,观察疗效。结果:患者均一次切除肿瘤,手术时间20~110 min,平均45 min,无并发症发生。术后随访1~3 a,复发15例,死亡3例,其中1例因肿瘤转移死亡,2例死于心、脑血管疾病。结论:动脉栓塞化疗联合钬激光切除治疗多发性膀胱肿瘤安全、简便,疗效满意,可提高患者生活质量。 Objective: To observe the curative effect of arterial embolization chemotherapy combined with holmium laser in the treatment of multiple bladder tumor. Methods: Thirty-six patients with multiple bladder tumor underwent internal iliac artery embolization and chemotherapy. After transurethral bladder tumor holmium laser surgery after 4 to 6 days, conventional intravesical instillation of pirarubicin was performed to observe the effect. Results: All the patients underwent tumor resection at one time. The operation time was 20 to 110 minutes, with an average of 45 minutes. No complications occurred. All cases were followed up for 1-3 years, 15 cases were relapsed and 3 died. One died of tumor metastasis and 2 died of heart and cerebrovascular disease. Conclusion: Arterial embolization chemotherapy combined with holmium laser in the treatment of multiple bladder cancer is safe, simple and effective, which can improve the quality of life of patients.