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目的:探讨胸腔镜胸膜固定术治疗大量恶性胸腔积液的临床疗效。方法:采用随机平行对照法将浚县人民医院收治的81例大量恶性胸腔积液的患者进行分组,对照组40例患者采用胸腔闭式引流术治疗,观察组41例患者采用胸腔镜胸膜固定术治疗。比较两组患者治疗后的临床疗效及并发症发生的情况。结果:观察组治疗后临床总有效率95.12%明显高于对照组80.00%,差异具有统计学意义(P<0.05)。观察组组治疗后并发症的总发生率4.88%明显低于对照组20.00%,差异具有统计学意义(P<0.05)。结论:胸腔镜胸膜固定术治疗大量恶性胸腔积液可提高临床总有效率,降低并发症的总发生率。
Objective: To investigate the clinical efficacy of thoracoscopic pleurodesis in the treatment of a large number of malignant pleural effusions. Methods: A total of 81 patients with malignant pleural effusion admitted to Xunxian People’s Hospital were divided into two groups according to randomized parallel control. Forty patients in the control group were treated by closed thoracic drainage. Thirty-one patients in the observation group were treated by thoracoscopic pleurodesis treatment. The clinical efficacy and complications of the two groups were compared. Results: After treatment, the total clinical effective rate in observation group was significantly higher than that in control group (95.12% vs 80.00%, P <0.05). The total incidence of complications in the observation group was 4.88% lower than that in the control group 20.00%, the difference was statistically significant (P <0.05). Conclusion: Thoracoscopic pleurodesis for the treatment of a large number of malignant pleural effusion can improve the total effective rate and reduce the overall complication rate.