测定了176例急性白血病细胞有丝分裂指数(MI)在各型白血病中的变化和对化疗的反应,结果ALL为15.62±3.12、ANLL为20.33±1.61,无显著性差异;各型中M_6最高,L_1最低;M_1仅次于L_1,与M_2a及L_2均有显著性差异,M_2、M_3和M_5各亚型间亦均有显著性差异.MI值与白血病细胞比例无明显相关,MI值在各级增生程度之间均无显著性差异;MI中位数以上者完全缓解率均高于MI中位数以下者,且ALL患者的MI与完全缓解率之间呈正相关(r=0.9998). The changes of mitotic index (MI) of 176 acute leukemia cells in all kinds of leukemia and the response to chemotherapy were determined. The results were ALL of 15.62 ± 3.12 and ANLL of 20.33 ± 1.61, with no significant difference; M_6 was the highest in all types, L_1 M_1, M_3, M_5 and M_5 subtypes were also significantly different.MI value was not significantly correlated with leukemia cell ratio, MI value at all levels of proliferation There was no significant difference between the two groups. The complete remission rate was higher than the median MI, and the MI was positively correlated with the complete remission rate (r = 0.9998).