目的 :探讨多发性骨髓瘤 (MM)骨髓涂片与活检联合应用在 MM诊断和治疗中的价值。方法 :31例 MM骨髓涂片采用瑞氏染色 ,骨髓活检采用塑料包埋法薄切片经 HGF染色。结果 :骨髓活检与骨髓涂片增生程度完全相符者占 48% ,活检高于形态者占 39% ,形态高于活检者占 13%。瘤细胞检出例数活检与形态完全相符者占 39% ,活检高于形态者占 48% ,形态高于活检者占 13%。结论 :骨髓涂片与活检结合可相互补充 ,对 MM诊断和治疗有十分重要的价值 Objective: To investigate the value of combined application of multiple myeloma (MM) bone marrow smear and biopsy in the diagnosis and treatment of MM. Methods: Thirty-one MM bone marrow smears were stained with Wright’s stain, and bone marrow biopsy was performed using plastic-embedded thin sections and stained with HGF. Results: Bone marrow biopsy accounted for 48% of those with bone marrow smear. The biopsy accounted for 39% of those with biopsy and 13% of biopsies. The number of tumor cells detected cases biopsy consistent with the morphology accounted for 39%, biopsy accounted for 48% higher than morphology, morphology was higher than the biopsy accounted for 13%. Conclusion: The combination of bone marrow smear and biopsy can complement each other, which is of great value in the diagnosis and treatment of MM