胃泌素(Gastrin,又称胃素或促胃液素)是胃窦和小肠上部G细胞分泌的一种重要的胃肠激素。早在1906年,Edkins就为它命了名,但对它的本质及其是否存在经历了近60年的反复争论。1964年Gregory和Tracy第一次把它提纯,并进而阐明化学结构和人工合成,这才确定了它是一种真正的激素。胃泌素的分子结构有多种形式,其中最通常而生物活性最强的形式是由17个氨基酸组成的小胃泌素(简称G17)。G17的存在又有两种类型:在第12位的酪氨酸有硫酸酯基团的称为胃泌素Ⅱ,没有此基团的称为 Gastrin (Gastrin, also known as gastrin or gastrin) is an important gastrointestinal hormone secreted by the antrum and upper G cells in the small intestine. As early as 1906, Edkins gave it a name, but has repeatedly argued for nearly 60 years about its nature and its existence. Gregory and Tracy first purified it in 1964, and then elucidated the chemical structure and synthetic, which confirmed it is a real hormone. The molecular structure of gastrin has many forms, of which the most common and most biologically active form is small gastrin (G17) consisting of 17 amino acids. The existence of G17 has two types: tyrosine at position 12 with a sulfate group called gastrin II, which is not known as