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目的:分析细菌感染中降钙素原的临床价值。方法:搜集2012年10月—2013年10月我院接收的脓毒血症22例作为A组,将细菌感染SIRS22例作为B组,将局部性细菌感染22例患者作为C组,将同期正常体检的健康人群22例作为D组。对四组进行降钙素原测定,并对比测定结果。结果:C组与D组降钙素原均处于正常范围。A组与B组相比较,降钙素原较高,差异显著,有统计学意义(P<0.05)。A组降钙素原水平治疗后较治疗前明显降低,差异显著,有统计学意义(P<0.05)。A组、B组全身性感染患者降钙素原特异性均高于WBC检测,差异较大,有统计学意义(P<0.05)。结论:降钙素原水平可以反映脓毒血症细菌感染程度,对全身性细菌感染的临床诊断特异性、敏感性较高,在早期诊断中具有极大的应用价值,值得推广。
Objective: To analyze the clinical value of procalcitonin in bacterial infection. Methods: Twenty-two cases of sepsis received in our hospital from October 2012 to October 2013 were selected as group A, 22 cases of bacterial infection SIRS as group B, 22 cases of localized bacterial infection as group C, Healthy people in the examination of 22 cases as a group D. Procalcitonin was measured in four groups and the results were compared. Results: C and D procalcitonin were in the normal range. Compared with group B, the level of procalcitonin in group A was higher, the difference was significant (P <0.05). The level of procalcitonin in group A was significantly lower after treatment than before treatment, with significant difference (P <0.05). The procalcitonin-specificities of patients with systemic infection in group A and group B were higher than that of WBC, with significant difference (P <0.05). CONCLUSION: The procalcitonin level can reflect the degree of bacterial infection of sepsis. It has a high sensitivity and specificity to the clinical diagnosis of systemic bacterial infection. It is of great value in early diagnosis and is worth popularizing.