采用正交实验设计的方法,对由猪胆汁钙盐法生产胆红素的工艺进行了探讨,使胆红素的收率比原工艺增加了约0.015%,以胆汁计可达0.045%左右。还证实在胆红素被氧化为胆绿素,在尚未进一步破坏的情况下,可通过补加过量的抗氧荆,配合调 pH,使再转变为胆红素。 Orthogonal experimental design method was used to investigate the process of producing bilirubin from pig bile calcium salt method. The yield of bilirubin was increased by about 0.015% compared with the original process and about 0.045% by bile. It has also been confirmed that bilirubin is oxidized to biliverdin, which can be converted to bilirubin by adding an excessive amount of anti-oxygen and supplementing the pH in the absence of further destruction.