口服给药主要通过胃肠道上皮细胞层经毛细血管壁吸收,由于小肠具有环状皱折和大量突起的绒毛,吸收面积大,酸碱度适中,蠕动快,血流量大,除一些弱酸性药物较多在胃中吸收外,大多数药物在小肠吸收。但由于药物的理化性质,胃肠道的pH,药物的剂型,进食等其他因素的影响,造成药物吸收不规则,药效出现的时间、强弱、持续时间不等。为了保证疗效,避免或减少不良反应,本文着重讨论服药时间对疗效的影响。目前医院一般药物多为一日三次给药,形成了 Oral administration mainly through the gastrointestinal epithelial cell layer by the capillary wall absorption, due to the small intestine with a ring of folds and a large number of protruding hair, absorption area, moderate pH, fast motility, blood flow, in addition to some weak acid drugs Mostly absorbed in the stomach, most drugs are absorbed in the small intestine. However, due to the physicochemical properties of drugs, gastrointestinal pH, drug dosage forms, eating and other factors, resulting in irregular absorption of drugs, pharmacodynamics appear time, strength, duration varies. In order to ensure efficacy, to avoid or reduce adverse reactions, this article focuses on the impact of medication time on the efficacy. At present, most of the general hospital drugs are given three times a day and formed