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目的探讨马来酸曲美布汀片联合美常安胶囊治疗肠易激综合征的疗效。方法将151例肠易激综合征患者随机分为3组,A组服用马来酸曲美布汀片和美常安胶囊,B组只服用马来酸曲美布汀片,C组只服用美常安胶囊。三组连续使用8周。结果马来酸曲美布汀联合美常安胶囊治疗组临床症状、大便性状明显改善,有效率94.12%,马来酸曲美布汀片组有效率为78.00%,美常安胶囊62.01%,经radit分析,P<0.05。结论马来酸曲美布汀片联合美常安胶囊治疗混合型肠易激综合征疗效好,不良反应小。
Objective To investigate the curative effect of Trimebutine maleate tablets and Mei Chang An Capsule on irritable bowel syndrome. Methods 151 cases of irritable bowel syndrome patients were randomly divided into three groups, A group taking trimebutine maleate tablets and the United States Changan capsule, B group only taking trimebutine maleate tablets, C group only taking the United States often capsule. Three consecutive use of eight weeks. Results The clinical symptoms of trimebutine maleate combined with Chang-An Capsule treatment group showed that the stool performance was significantly improved with an effective rate of 94.12%. The effective rate of trimebutine maleate tablets group was 78.00% and that of Chang-an-an Capsule group was 62.01% Analysis, P <0.05. Conclusion Trimebutine maleate tablets combined with Chang-An Capsule in the treatment of mixed irritable bowel syndrome has good curative effect with small adverse reactions.