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Skp2在多数恶性肿瘤中呈高表达。研究发现,Skp2与恶性肿瘤的发生发展密切相关。全文就Skp2的结构特点、生物学活性、作用机制及其与恶性肿瘤的预后及治疗关系的研究进展作一综述。
Skp2 is highly expressed in most malignant tumors. The study found that Skp2 and the occurrence and development of malignant tumors are closely related. This review summarizes the structural features, biological activity, mechanism of action of Skp2 and its relationship with the prognosis and treatment of malignant tumors.