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为了解福建省人群丙型肝炎流行特征,于1992年进行丙型肝炎感染的血清流行病学调查。采用多阶段分层整群随机抽样法,采集福建省疾病监测点自然人群的1237户家庭中3809例血清标本。应用UBIEIA法检测。结果显示HCV标化流行率为3.99%,男性3.63%,女性4.25%;城市3.12%,农村460%;10岁以下较低,峰值在20岁左龄组。年龄问、性别间、城乡间无差异;地区间差异显著,最高为6.08%,最低1.39%。家庭内传播并不重要,无家庭聚集性现象。存在HCV与HAV、HBV、HEV的重叠感染。丙肝感染与输血史、肝病史无显著相关。95.4%丙肝感染者无输(受)血史。结果提示福建省自然人群HCV传播主要经输血以外途径散发性感染。
To understand the epidemiological characteristics of hepatitis C among the population in Fujian Province, a serological epidemiology investigation of hepatitis C infection was conducted in 1992. A total of 3,809 serum samples were collected from 1237 households in the natural population of the disease surveillance sites in Fujian Province using multi-stage stratified cluster random sampling method. UBIEIA method test. The results showed that the prevalence of HCV was 3.99%, 3.63% for males and 4.25% for females; 3.12% for urban areas and 460% for rural areas; lower than 10 years old and peaked at 20 years old. There was no difference in age, gender, urban and rural areas. The differences among the regions were significant with the highest 6.08% and the lowest 1.39%. Family communication is not important, there is no family aggregation phenomenon. There are overlapping infections of HCV and HAV, HBV and HEV. Hepatitis C infection and blood transfusion history, history of liver disease no significant correlation. 95.4% of hepatitis C infection without losing (by) blood history. The results suggest that the natural transmission of HCV in Fujian Province is mainly caused by sporadic infection outside blood transfusion.