目的 copd合并曲霉菌感染导肺部重症感染是临床常见重症,死亡率高,病程凶险。本课题旨在证明复方鲜竹沥口服液、参麦注射液,配伍伏立康唑使用对于此种感染的治疗效果优于单纯使用伏立康唑的疗效。方法将66例患者随机分为两组每组33例,实验组服用伏立康唑和复方鲜竹沥口服液,并注射参麦针,对照组只服用伏立康唑。疗程结束后,从咳嗽,咳痰,胸闷气急,乏力四个方面的改善情况比较两组疗效。结果实验组咳嗽,咳痰,乏力情况改善优于对照组,胸闷气急改善情况两组统计学无明显差异。结论对于copd并发肺部曲霉菌感染,伏立康唑,复方鲜竹沥口服液配伍使用的疗效优于单独使用伏立康唑的疗效。在对copd合并曲霉感染病人临床治疗中可以考虑使用此种配伍用药疗法。 Objective Copd infection with Aspergillus infection leading to severe pulmonary infection is a common clinical severe, high mortality, dangerous course. The purpose of this project is to prove that the compound XZZL oral solution, Shenmai injection and Voriconazole are more effective than Voriconazole for the treatment of this infection. Methods Sixty-six patients were randomly divided into two groups of 33 patients in each group. Voriconazole and compound XZL were used in the experimental group and Shenmai injection was administered in the control group, and voriconazole was administered in the control group. After treatment, from the cough, expectoration, chest tightness, shortness of breath, fatigue four aspects of the improvement compared between the two groups curative effect. Results The improvement of cough, sputum and fatigue in the experimental group was better than that of the control group. There was no significant difference between the two groups in the improvement of chest tightness and shortness of breath. Conclusions For copd complicated with pulmonary aspergillosis, the effect of voriconazole and compound xuzhuliu oral solution is better than that of voriconazole alone. In copd with Aspergillus infection in patients with clinical treatment can consider the use of such compatibility medication.