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目的探讨弥散张量成像技术(DTI)融合血氧水平依赖成像技术(BOLD)指导脑功能区肿瘤神经导航手术的临床应用价值。方法我院在2011年12月-2015年12月收治37例涉及运动区的脑肿瘤患者,按随机数字表法将其分为试验组(DTI融合BOLD影像导航)19例及对照组(仅DTI影像导航)18例,两组患者均行脑功能区肿瘤神经导航术,利用SPSS 19.0统计两组患者手术效果及预后情况。结果对照组肿瘤全切率50%低于试验组肿瘤全切率73.68%(P<0.05);对照组术后致残率61.11%高于试验组术后致残率36.84%(P<0.05);预后评估:对照组KPS评分(79.11±13.14)分低于试验组KPS评分(90.00±4.88)分,对照组优良率38.90%低于试验组优良率63.20%(P<0.05)。结论 DTI联合BOLD技术应用于功能区脑肿瘤的导航手术,能更清晰地显示脑功能区的解剖学信息,有利于最佳手术入路及手术方案的设计,对提高肿瘤的全切率及最大限度地保留运动功能具有重要的价值。
Objective To investigate the clinical value of diffuse tensor imaging (DTI) combined with oximetry-dependent imaging (BOLD) in guiding neurofunctional navigation in brain functional areas. Methods From December 2011 to December 2015, 37 patients with brain tumors involving motor area were enrolled in this study. They were divided into experimental group (DTI fusion BOLD image navigation) and control group (DTI only) by random number table method Image navigation) 18 cases, two groups of patients underwent brain tumor neurotopography navigation, the use of SPSS 19.0 statistics of the two groups of patients with surgical results and prognosis. Results The total resection rate of the control group was 50% lower than that of the experimental group (73.68%, P <0.05). The postoperative morbidity of the control group was 61.11%, which was 36.84% (P <0.05) ; The prognosis evaluation: The control group KPS score (79.11 ± 13.14) points lower than the test group KPS score (90.00 ± 4.88) points, the control group 38.90% excellent and good rate was 63.20% (P <0.05). Conclusion The combination of DTI and BOLD technique in navigation of functional brain tumors can display the anatomical information of brain functional areas more clearly and is beneficial to the design of the optimal surgical approach and surgical plan. It is of great value to retain the motor function to a limited extent.