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目的探讨经脑动脉内注溶栓药物治疗急性闭塞性脑血管病的临床效果。材料与方法本组２１例。起病至溶栓治疗时间３～２０小时。采用微导管技术将导管超选至靶血管闭塞点或闭塞血管起始段。尿激酶用量不超过１００万单位，灌注溶栓时间最大不超过２小时。结果灌注溶栓治疗后脑血管造影复查，闭塞时间６小时内的９例中，完全再通７例。闭塞时间超过６小时的１２例，完全再通６例。总计治愈８例，显效５例，有效４例，无效４例，其中１例死亡。结论动脉内灌注溶栓药物治疗急性闭塞性脑血管病效果满意。
Objective To investigate the clinical effect of intra-arterial injection of thrombolytic drugs in the treatment of acute occlusive cerebrovascular disease. Materials and Methods The group of 21 cases. From onset to thrombolytic treatment time 3 to 20 hours. Micro catheter technique is used to superselect the target vessel occlusion or occlusion of the beginning of the vessel. Urokinase dosage does not exceed 1 million units, the maximum perfusion thrombolytic time does not exceed 2 hours. Results Cerebral angiography was performed after perfusion and thrombolysis. Of the 9 patients within 6 hours of occlusion, 7 were completely recanalized. 12 cases occluded for more than 6 hours and completely recanalized in 6 cases. A total of 8 cases were cured, markedly effective in 5 cases, effective in 4 cases, 4 cases were ineffective, of which 1 case died. Conclusion Intra-arterial infusion of thrombolytic drugs in patients with acute obliterative cerebrovascular disease with satisfactory results.