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目的：研究硫酸普拉酮钠促宫颈成熟作用的临床价值。方法：选择１２０例足月妊娠宫颈未成熟或未完全成熟的孕产妇，随机分为两组，每组６０例，观察组应用硫酸普拉酮钠，对照组应用苯甲酸雌二醇，对比观察两组宫颈Ｂｉｓｈｏｐ评分、产程进展、产后出血、新生儿Ａｐｇａｒ评分。结果：观察组促宫颈成熟有效率明显增高（Ｐ＜０．０５），第一产程活跃期缩短（Ｐ＜０．０５）；两组产妇出血量及新生儿Ａｐｇａｒ评分无明显差异（Ｐ＞０．０５）。结论：硫酸普拉酮钠是一种安全、有效的促宫颈成熟剂。
Objective: To study the clinical value of promoting the maturation of cervix with pullulan sodium sulfate. Methods: 120 pregnant women with incomplete or incomplete mature pregnancy were randomly divided into two groups (n = 60 in each group). The observation group was given sodium pkasone sulfate and the control group was estradiol benzoate. Two groups of cervical Bishop score, labor progress, postpartum hemorrhage, neonatal Apgar score. Results: The effective rate of cervical ripening in observation group was significantly higher (P <0.05), and the active stage of the first stage of labor was shorter (P <0.05). There was no significant difference between the two groups in the amount of bleeding and Apgar score .05). Conclusions: Phenylketone sulfate is a safe and effective cervical ripening agent.