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目的探讨地佐辛复合异丙酚用于妇科宫腔镜手术麻醉中的效果和安全性。方法选取行宫腔镜手术妇科患者60例,ASA分级Ⅰ-Ⅱ级,随机分为两组:地佐辛复合异丙酚组(A组,n=30),异丙酚组(B组,n=30)。记录两组患者麻醉前(T0)、麻醉后2min(T1)、扩宫颈时(T2)、术毕(T3)、清醒后5min(T4)时MAP、SpO2、HR,同时记录两组患者呼吸抑制的发生例数、术后疼痛的程度和异丙酚的用量。结果两组患者麻醉前MAP、HR、SpO2比较差异无显著性(P>0.05);T1时与T0时比较MAP、HR、SpO2下降,MAP、HR有显著性差异(P<0.05),SpO2差异无显著性(P>0.05);两组间各时点比较差异无显著性(P>0.05);两组麻醉起效时间、意识恢复时间及呼吸抑制例数差异无显著性(P>0.05);丙泊酚用量和术后疼痛的例数,B组大于A组,有显著性差异(P<0.05)。结论地佐辛与异丙酚复合麻醉在妇科宫腔镜手术中效果满意,适宜应用。
Objective To investigate the effect and safety of dezocine combined with propofol in gynecological hysteroscopic anesthesia. Methods Sixty patients undergoing hysteroscopic gynecological surgery were randomly divided into two groups: dezocine combined with propofol (group A, n = 30), propofol group (group B, n = 30). The MAP, SpO2 and HR were recorded before anesthesia (T0), 2min after anesthesia (T2), T2 (T2), T3 (T3) and 5min The number of cases occurred, the degree of postoperative pain and the amount of propofol. Results There was no significant difference in MAP, HR and SpO2 before anesthesia between the two groups (P> 0.05). Compared with T0, MAP, HR and SpO2 were decreased, MAP and HR were significantly different (P <0.05) (P> 0.05). There was no significant difference between the two groups at each time point (P> 0.05). There was no significant difference between the two groups in onset of anesthesia, recovery of consciousness and the number of respiratory depression cases (P> 0.05) ; Propofol dosage and the number of cases of postoperative pain, B group than in A group, there was a significant difference (P <0.05). Conclusion The combination of dezocine and propofol anesthesia in gynecological hysteroscopic surgery with satisfactory results, suitable for use.