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目的和方法：人孔头瘤病毒16、18型感染与宫颈癌及阴茎癌的发生有密切关系，从预防角度出发，我们采用PCR－DNA扩增的方法，检测了48例包皮环切标本中HPV6，11，16，18，33型的DNA保守片段。结果：20例阳性，阳性率为41．7％。按年龄、有无包皮垢及有无感染史分组，各组间均无显著性差异。结论：主张男孩应尽早行包皮环切术。
Aims and methods: Human papulomavirus 16 and 18 infections are closely related to the occurrence of cervical cancer and penile cancer. From the perspective of prevention, we used PCR-DNA amplification to detect 48 cases of circumcision specimens. DNA conserved fragments of HPV 6,11,16,18,33. Results: 20 cases were positive, the positive rate was 41.7%. There was no significant difference between groups according to age, presence of smegma, and history of infection. Conclusion: It is advocated that boys should perform circumcision as soon as possible.