论文部分内容阅读
目的观察前列地尔序贯疗法治疗老年临床期糖尿病肾病患者的临床疗效。方法本文选取70例老年临床期糖尿病肾病患者,随机划分两组,对照组采用常规疗法,治疗组采用前列地尔序贯疗法,对比两组的临床疗效、肾损害指标改善情况。结果治疗组治疗后的24h尿蛋白定量、尿素氮、血肌酐三项肾损害相关指标分别是(1.28±1.10)g/d、(5.32±1.08)mmol/l、(73.08±14.07)umol/l,和对照组治疗前、治疗后、治疗组治疗前对应的肾功能相关指标大小对比存在显著性差异(P<0.05)。结论前列地尔序贯疗法,可以明显改善患者临床症状,甚至较少尿蛋白及改善肾功能,提高治疗效果。
Objective To observe the clinical efficacy of sequential therapy of alprostadil in the treatment of geriatric diabetic nephropathy. Methods Seventy elderly diabetic patients with diabetic nephropathy were randomly divided into two groups. The control group was treated by conventional therapy. The treatment group was treated with alprostadil sequential therapy. The clinical curative effect and the improvement of renal damage index were compared. Results The indexes of urinary protein, urea nitrogen and serum creatinine in the treatment group were (1.28 ± 1.10) g / d, (5.32 ± 1.08) mmol / l, (73.08 ± 14.07) umol / l (P <0.05). There was significant difference between the control group before treatment and after treatment, the treatment group before treatment corresponding renal function related indicators size. Conclusions Alprostadil sequential therapy can significantly improve the patient’s clinical symptoms, even less urinary protein and improve renal function, improve the therapeutic effect.