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目的探讨无创正压通气在治疗慢性阻塞性肺疾病并发II型呼吸衰竭中的疗效。方法 84例慢性阻塞合并Ⅱ型呼吸衰竭患者按家属充分知情自愿原则分为对照组与观察组,各42例,对照组采用常规改善心功能、纠正酸碱平衡、体内电解质紊乱等,观察组在对照组基础上使用无创呼吸机进行正压通气辅助性治疗,对比两组患者的疗效以及血气情况。结果观察组治疗效果显著优于对照组(χ2=7.786,P=0.020),观察组在pH值、PaO2、PaCO2及RR改善程度上显著优于对照组(P<0.05)。结论无创正压通气在治疗慢性阻塞肺疾病合并II型呼吸衰竭疗效肯定,具有无创性、并发症少、同步性能好、操作简单等优势,可作为治疗一线方案。
Objective To investigate the curative effect of non-invasive positive pressure ventilation in treating type II respiratory failure of chronic obstructive pulmonary disease. Methods Eighty-four patients with chronic obstructive pulmonary hypertension and type Ⅱ respiratory failure were divided into control group and observation group according to the principle of family members’ full and voluntary consent, 42 cases in each group. The control group was given routine improvement of cardiac function, acid-base balance correction, electrolyte imbalance in vivo, Control group based on the use of noninvasive ventilator positive pressure ventilation adjuvant therapy, the two groups were compared the efficacy and blood gas conditions. Results The observation group was significantly better than the control group (χ2 = 7.786, P = 0.020). The observation group was significantly better than the control group in the improvement of pH, PaO2, PaCO2 and RR (P <0.05). Conclusion Non-invasive positive pressure ventilation in the treatment of chronic obstructive pulmonary disease with type II respiratory failure positive effect, with non-invasive, less complications, good synchronization, simple operation and other advantages, can be used as a first-line treatment program.