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类风湿性关节炎(RA)是一种常见的风湿免疫性疾病,由于非甾体抗炎药(NSAID)的不规范使用,合并消化性溃疡病人较多,目前仅推荐奥湿克作为合并溃疡的风湿病用药,但该药价格较高。萘丁美酮是一种非酸性药物,胃肠道相对安全,但治疗合并溃疡的RA是否安全目前国内外尚无报道,我们在严密观察下试用萘丁美酮联合小剂量奥美拉唑治疗合并溃疡的RA,观察关节疼痛临床疗效,定期复查胃镜观察溃疡变化以了解其胃肠道安全性。1材料与方法1.130例均为本院门诊和住院患者,RA的诊断根据美国风湿病学会的临床及放射学依据,均经胃镜检查确诊为消化性溃疡的RA活动期患者,近2周未服用非甾体抗炎药,告知
Rheumatoid arthritis (RA) is a common rheumatic autoimmune disease. Due to the non-standard use of non-steroidal anti-inflammatory drugs (NSAIDs), there are more patients with peptic ulcer. Currently, only rheumatoid arthritis is recommended as a combined ulcer Rheumatism medication, but the drug prices higher. Nabumetone is a non-acidic drugs, gastrointestinal tract is relatively safe, but the treatment of ulcers with RA is safe at home and abroad have not been reported at present, we closely test the trial of nabumetone combined with low-dose omeprazole Combined with ulcer RA, observe the clinical efficacy of joint pain, regular review of gastroscopy observed ulcer changes in order to understand its gastrointestinal tract safety. 1 Materials and Methods 1.130 cases were hospital outpatient and inpatient, RA diagnosis according to the American College of Rheumatology clinical and radiographic basis, were confirmed by gastroscopy RA patients with peptic ulcer disease in the past two weeks did not take Non-steroidal anti-inflammatory drugs, told