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生长激素(GH)缺乏症的诊断是由放射免疫法(RIA)测定刺激后的血中GH或连续24小时静脉血标本作出的。本文作者报告4名健康非肥胖儿童用RIA测定血中GH明显缺乏,而其生长速率则正常,故诊断为难测性生长激素综合征。 4名受检儿童年龄为6.2至13.9岁。其中1名诊断为肢端肥大症,另3名均因身材矮小而诊断为GH缺乏,4名儿童身高分别为同年龄正常儿童身高的第95、5、10和25百分位数,其骨龄均落后实际年龄2岁。其中2名进行精氨酸-胰岛素低血糖刺激试验,用RIA法检测,GH峰值≥10ng/ml。所有儿童均检测24小时GH值,RIA法检测GH值为1.0～1.7
The diagnosis of growth hormone (GH) deficiency is determined by radioimmunoassay (RIA) of stimulated blood GH or continuous 24-hour venous blood samples. The authors report that four healthy non-obese children with RIA determination of blood was significantly lack of GH, and its growth rate was normal, it is diagnosed as difficult to detect growth hormone syndrome. Four subjects were aged 6.2 to 13.9 years old. One was diagnosed as acromegaly and the other three were diagnosed with GH deficiency due to short stature. The height of the four children were the 95th, the 5th, the 10th, the 25th and the 25th percentiles, respectively, of the normal children of the same age. Are behind the actual age of 2 years old. Two of them were tested for arginine-insulin hypoglycemia and were detected by RIA method with a peak GH value of ≥10 ng / ml. All children were detected 24 hours GH value, RIA method to detect GH value of 1.0 to 1.7