动脉粥样硬化(AS)是严重危害人类健康的常见病与多发病,欧美国家疾病致死原因的50%以上与AS密切相关,我国近年来AS的发病率也呈现逐年上升和年轻化的趋势[1]。大量研究资料表明,血浆高密度脂蛋白(HDL)具有抗AS作用,可使血管壁减少与有致粥样硬化颗粒的接触。2003年的一项临床研究也首次证实了HDL在人体内具有确切的抗AS作用[2]。载 Atherosclerosis (AS) is a serious risk to human health, common and frequently-occurring disease in Europe and the United States more than 50% of the causes of disease and AS are closely related to the incidence of AS in China in recent years also showed a trend of increasing year by year and younger [ 1]. A large number of research data show that plasma high-density lipoprotein (HDL) has anti-AS effect, can reduce the vessel wall and atherogenic particles of contact. A 2003 clinical study also confirmed for the first time that HDL has an exact anti-AS effect in humans [2]. Contained